Boston Red Sox vs Arizona Diamondbacks Forecast, 9/5/2025 MLB Predictions, Top Picks & Odds

Home » Boston Red Sox vs Arizona Diamondbacks Forecast, 9/5/2025 MLB Predictions, Top Picks & Odds

Matchup: Boston Red Sox vs Arizona Diamondbacks

Date: Friday, September 5, 2025

Venue: Chase Field, Phoenix, AZ

Broadcast: DBACKS.TV

Betting Odds: Boston (-160) Arizona (+132)

This Friday, Chase Field will host the Arizona Diamondbacks (70-71) as they take on the Boston Red Sox (78-63). The current betting odds favor the Red Sox at -160, while the Diamondbacks are placed at +132. The total runs line is set at 8. The starting pitchers for the game are Lucas Giolito and Eduardo Rodriguez.

MLB betting predictions for Ketel Marte and the Arizona Diamondbacks

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The Red Sox currently maintain a slugging percentage of .426 and have struck out 1,245 times while accumulating 456 walks. Boston has achieved 664 RBIs and 1,231 hits throughout the season, with a team batting average of .254. They have also recorded 283 doubles and hit 169 homers, ranking 5th in the league with 696 runs scored and an on-base percentage (OBP) of .325. The Red Sox average 4.9 runs per game.

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The Red Sox boast a strikeout-to-walk ratio of 2.52 and their pitching ranks feature a WHIP of 1.29. This season, the pitching staff has allowed 145 home runs and 595 runs total (13th in the league). They have given up 1,165 hits (8.3 per 9 innings) and 524 earned runs, leading to a team ERA of 3.73 (5th in MLB) and 1,166 strikeouts. With 462 walks issued, their FIP stands at 4.04.

Red Sox relievers have faced opponents on base 139 times and participated in 169 high-pressure situations, currently achieving 76 holds (18th in MLB). They have a save conversion rate of 62.5%, occurring in 142 save opportunities, with 40 successful saves and 24 blown chances. Out of 187 inherited runners, 32.6% have scored. The Red Sox have utilized 462 relief pitchers this season.

In 11,367 innings, the Red Sox have managed to convert 69.2% of balls in play into outs, ranking 21st in MLB. The Baltimore Orioles have recorded 3,789 putouts, 1,289 assists, and committed 105 errors, with a fielding percentage of .980, the lowest in baseball, while executing 115 double plays.

Giolito has pitched 1,138 innings with a career total of 1,182 strikeouts. With a career record of 71-64, he holds a FIP of 4.25, having faced 4,780 batters in the big leagues. He has an earned run average of 4.32 (546 ERs allowed) and a WHIP of 1.252. Throughout his career, he has allowed 997 hits (7.9 hits per nine innings) and issued 428 walks.

This year, the Arizona Diamondbacks exhibit an OBP of .322 and a batting average of .249. They have struck out 1,144 times (18th in MLB) and achieved 1,189 hits, along with 194 home runs and 676 RBIs. With a SLG of .436, they average 4.91 runs per game (6th in the league). The Diamondbacks have recorded 240 doubles, 468 walks, and scored 692 runs.

Arizona’s pitching staff has allowed 673 runs this season, with a team ERA of 4.45 (621 earned runs). They have given up 167 home runs and relinquish 4.83 runs per 9 innings (23rd in MLB) with a team WHIP of 1.326 and a FIP of 4.26. Their strikeout-to-walk ratio currently stands at 8.00 (1,122 strikeouts against 440 walks), ranking them 25th in total hits allowed with 1,225.

Diamondbacks relievers have a 30.6% inherited score rate from 160 inherited runners. They have been called into 141 high-leverage situations and have faced runners on base 125 times. The team has 148 save opportunities, achieving 78 holds and 26 blown saves, with a save rate of 60.6%, ranking 22nd in the league. A total of 431 relief pitchers have taken the mound this season, contributing to 40 saves from 66 opportunities.

The Arizona Diamondbacks have executed 110 double plays with a fielding percentage of .986 (14th in MLB). They have recorded 1,269 assists, made 70 errors, and achieved 3,767 putouts during the current season. In 11,301 innings played, their defensive efficiency stands at 69.3% (20th in professional baseball).

Eduardo Rodriguez has allowed 1,254 hits in his MLB career, recording 1,274 strikeouts in 1,275 innings pitched. With a career record of 91-65, he has a career earned run average of 4.21, allowing 8.9 hits per nine innings and conceding 596 earned runs. He has a WHIP of 1.333 and a FIP of 4.1, with a strikeout-to-walk ratio of 2.86, facing 5,458 batters throughout his professional career.

Who do you think will take tonight’s MLB matchup against the spread or moneyline?

Guy Bruhn’s Prediction: Bet on Boston (-160)

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