San Diego Padres at Chicago White Sox Forecast, 9/20/2025 MLB Selections, Top Wagers & Odds

Home » San Diego Padres at Chicago White Sox Forecast, 9/20/2025 MLB Selections, Top Wagers & Odds

Matchup: San Diego Padres vs Chicago White Sox

Date: Saturday, September 20, 2025

Venue: Rate Field, Chicago, IL

Broadcast: Chicago Sports Network

Betting Odds: San Diego (-132) Chicago (+110)

Rate Field will host an exciting encounter as the Chicago White Sox (57-96) aim to take down the San Diego Padres (83-69) this Saturday. The moneyline odds reflect the Padres at -132 and the White Sox at +110. The game’s total runs over/under is set at 9, with Yu Darvish and Yoendrys Gomez slated to start as pitchers.

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As a team, the Padres bring a slugging percentage of .390 and have recorded 1,075 strikeouts, while achieving 484 walks. They’ve accumulated a total of 614 RBIs and have delivered 1,281 hits this season, leading to a batting average of .252. The Padres have notched 244 doubles and hit 140 home runs, totaling 651 runs scored and an on-base percentage of .322. Their scoring average stands at 4.3 runs per game, positioning them at 20th in the league.

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The Padres possess a stellar team ERA of 3.67, ranking 3rd in MLB, accompanied by an impressive 1,332 strikeouts from their pitching staff. This year, Padres pitchers have given up 169 home runs and a total of 590 runs (2nd in MLB). While allowing 488 walks, their FIP stands at 4.03 overall. The team has let up 1,128 hits (7.6 per 9 innings) and recorded 548 earned runs. Their strikeout-to-walk ratio is 2.73, and the combined WHIP for the pitchers is 1.20.

In high-pressure situations, Padres bullpen pitchers have entered the game 173 times, achieving 198 high-leverage situations. Their bullpen has secured 98 holds this season (6th in MLB) and boasts a 74.6% save percentage through 166 save opportunities, garnering 47 saves while blowing 16 of 63 chances. They’ve also inherited 244 base runners, of which 29.1% have scored. A total of 536 relief pitchers have taken the mound this season.

Defensively, the Padres have converted 71.7% of balls in play into outs, putting them 2nd in the league. Their season tally includes 4,029 putouts, 1,143 assists, and 70 errors, leading to a fielding percentage of .987, ranking 12th overall in MLB, and they have executed 107 double plays.

Yu Darvish has pitched 1,768 innings with 2,067 career strikeouts. Holding a record of 114-93, Darvish has a FIP of 3.59 as he has faced 7,266 batters in the majors. With an ERA of 3.65 (717 earned runs allowed) and a WHIP of 1.136, he has permitted 1,448 hits (7.4 hits per nine innings), along with 561 walks.

The Chicago White Sox currently hold a team on-base percentage of .302 and a batting average of .233 for the season. Striking out 1,287 times (14th in MLB), they’ve managed to secure 1,184 hits. The White Sox have accumulated a total of 154 home runs and 588 RBIs this season. Their slugging percentage stands at .373, averaging 3.98 runs per game (26th in MLB). This team has also recorded 231 doubles, issued 472 walks, and scored 609 runs in total.

Defensively, the White Sox pitching staff has permitted 698 runs this year, holding an ERA of 4.23 (629 earned runs allowed). They have surrendered 175 home runs, averaging 4.69 runs per 9 innings (21st in MLB). Their WHIP is at 1.362, while their FIP currently stands at 4.49. The strikeout-to-walk ratio of their pitching unit is 8.00, with 1,193 strikeouts against 566 walks. Chicago ranks 15th in the league for total hits allowed, tallying 1,256.

In save situations, Chicago’s bullpen has registered 23 saves from 44 opportunities, ranking 29th in the MLB with a save rate of 52.3%. They’ve sent 498 relievers to the mound this season, with bullpen pitchers appearing in 141 high-pressure situations and 154 with runners on base. The inherited runner percentage sits at 31.8% from 223 inherited runners, with the White Sox recording 64 holds and 21 blown saves across 110 save chances.

Defensively, the Chicago White Sox have completed 123 double plays and hold a fielding percentage of .982 (28th in MLB). They have amassed 1,208 assists and 96 errors this season, contributing to a total of 4,015 putouts in their 12,045 innings played. Their defensive efficiency stands at 69.8%, ranking 18th in Major League Baseball.

So far in his major league career, Gomez has allowed 58 hits while notching 63 strikeouts over 64 innings of work. He has surrendered 33 earned runs, maintaining a WHIP of 1.433 and a FIP of 4.6. His strikeout-to-walk ratio stands at 1.85 as he has faced 293 batters in his professional baseball career. With a record of 3-2, Gomez holds a career ERA of 4.63, giving up 8.1 hits per nine innings.

Who will come out on top in tonight’s MLB matchup against the spread or moneyline?

Pick by Josh Schonwald: Bet on San Diego (-132)

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