Iowa State Cyclones vs. Arizona Wildcats Analysis, 10/24/2026 College Football Picks, Top Bets & Odds

Home » Iowa State Cyclones vs. Arizona Wildcats Analysis, 10/24/2026 College Football Picks, Top Bets & Odds

  • Matchup: Iowa State Cyclones vs. Arizona Wildcats
  • Event Date: Saturday, October 24, 2026
  • Venue: Casino Del Sol Stadium, Tucson, AZ
  • Broadcast: ESPN2
  • Point Spread: Wildcats favored by (-10.5)
  • Total Points: Over/Under set at 51

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The Arizona Wildcats (5-1) are set to host the Iowa State Cyclones (3-3) on Saturday, October 24, 2026, at the Casino Del Sol Stadium. Sportsbooks have installed the Wildcats as 10.5-point favorites, with the over/underline at 51 points.

The Iowa State Cyclones have a record of 3-3 this season. In their latest outing, the Cyclones faced off against the BYU Cougars but fell short, losing 24-10. Defensively, Iowa State struggled against the run, allowing 177 yards on 31 carries, translating to an average of 5.7 yards per rush. The Cyclones permitted 22 completions on 30 attempts, yielding 329 passing yards with a completion rate of 73.3%. Overall, Iowa State managed 200 offensive yards on 56 plays, with a rushing game that accounted for 102 yards over 27 carries, averaging 3.8 yards per carry.

College football predictions Iowa State Cyclones

In terms of scoring, the Iowa State Cyclones are averaging 29.7 points per game. Their rushing offense averages 181.5 yards per game, placing them 47th nationally. With 2,158 total yards compiled this season, the Cyclones have amassed 9 passing touchdowns and 11 rushing touchdowns. Their offense has also achieved 115 first downs, although they have faced 32 penalties totaling 282 yards and have surrendered possession 5 times this year.

On the defensive side, the Cyclones have conceded 1,191 passing yards, ranking 33rd in the nation. They allow an average of 198.5 passing yards per game with a completion percentage against of 63.4%. Overall, Iowa State’s defense allows 352.3 total yards per game, ranking them 66th in college football. The defense has given up 7 passing touchdowns and 9 rushing touchdowns, with opponents averaging 4.4 yards per carry and 153.8 rushing yards per game, totaling 923 rushing yards surrendered over 6 games. Iowa State’s defense ranks 51st in Division 1, allowing 21.7 points per game.

The Arizona Wildcats bring a record of 5-1 into this contest. In their previous match, they triumphed over the West Virginia Mountaineers with a score of 52-31. The Wildcats averaged 5.2 yards per carry, racking up 141 rushing yards on 27 attempts. Overall, Arizona amassed 482 total yards through 51 plays, averaging 9.5 yards per play. Their passing defense gave up a completion rate of 39.3%, allowing 219 yards on 11 completions out of 28 attempts, while their run defense conceded 303 yards on 76 attempts (4.0 yards per carry).

On the scoring front, the Wildcats average 35.7 points per game, placing them 29th nationally. Arizona’s offense generates an average of 456.5 yards per game, ranking 21st. This season, the Wildcats have accumulated a total of 341 yards from penalties over 36 infractions, which ranks 103rd in the nation. They have thrown 6 interceptions, lost 2 fumbles, and registered 143 first downs. Over the course of the season, Arizona has accumulated 1,840 passing yards, averaging 306.7 passing yards per game, a ranking of 10th in college football, alongside an average of 149.8 rushing yards, totaling 899 rushing yards.

Defensively, Arizona has allowed 698 rushing yards (116.3 yards per game) and 8 rushing touchdowns this season. In terms of the passing game, they have given up 5 touchdowns and 214.2 passing yards per game, ranking them 74th in Division 1. The Wildcats have allowed 114 total points this season. The defense has recorded 3 fumble recoveries and 2 interceptions throughout the season and has been on the field for 407 plays, placing them 50th in Division 1. Arizona is allowing an average of 19.0 points per game, ranking them 32nd in college football.

Which team will emerge victorious in tonight’s matchup between the Cyclones and Wildcats?

Tip: Bet on the Wildcats -10.5

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Pick: Arizona Wildcats -10.5
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