Oregon Ducks vs Oklahoma State Cowboys Betting Insights, 9/12/2026 College Football Picks, Top Bets & Odds

Home » Oregon Ducks vs Oklahoma State Cowboys Betting Insights, 9/12/2026 College Football Picks, Top Bets & Odds

  • Matchup: Oregon Ducks vs Oklahoma State Cowboys
  • Date: Saturday, September 12, 2026
  • Venue: Boone Pickens Stadium, Stillwater, OK
  • Broadcast: ESPN+
  • Betting Odds: Cowboys (+22.0)
  • Point Total: 56.5

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This Saturday, September 12, 2026, the Oklahoma State Cowboys (0-1) will face off against the Oregon Ducks (1-0) at Boone Pickens Stadium. The Ducks are opening as 22-point favorites according to betting lines, with a total set at 56.5 points.

The Oregon Ducks arrive at this matchup with a record of 1-0 after their recent triumph over the Boise State Broncos, winning 34-27. In that game, Oregon’s offense executed 25 rushing attempts for 119 yards, averaging 4.8 yards per carry, and completed a total of 497 yards across 63 plays. The defense allowed 15 completions on 29 attempts for 181 yards, posting a 51.7% completion rate against them. On the ground, the Ducks gave up 93 yards on 36 carries, averaging 2.6 yards per rush.

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On the offensive side, the Ducks have been averaging 34.0 points per game. They are generating around 119.0 rushing yards, placing them 99th in Division 1. In terms of total yards, Oregon has accumulated 497 so far this season. They’ve scored 3 touchdowns through the air and 1 on the ground. As a team, the Ducks have achieved 18 first downs and committed 10 penalties for 90 yards, alongside 1 turnover.

Defensively, Oregon ranks 100th in the nation, surrendering 27.0 points per game. They allow an average of 2.6 yards per rush and have given up 93 rushing yards across 1 game. In passing defense, the Ducks have permitted 181 yards, placing them 60th in Division 1, with a 51.7% completion rate against them. Overall, they are yielding 274.0 yards per game, sitting at 54th in the nation, allowing 3 passing touchdowns and no rushing touchdowns so far.

The Cowboys enter this matchup with a record of 0-1. In their previous outing, they suffered a defeat against the Tulsa Golden Hurricane, losing 24-10. The Oklahoma State offense managed 368 yards, running 86 plays at an average of 4.3 yards per play. They averaged 3.4 yards per rush, totaling 127 yards on 37 attempts. Defensively, they allowed 134 yards on 33 rushing attempts, averaging 4.1 yards per rush, while the secondary faced a completion rate of 70.8%, giving up 227 yards on 17 completions out of 24 passing attempts.

In terms of scoring, the Cowboys currently stand at 123rd in Division 1 with 10.0 points per game. They average 368.0 total yards per outing, placing 89th nationally. Oklahoma State has incurred 59 penalty yards due to 6 infractions, ranking 85th in Division 1. They’ve thrown 2 interceptions and lost 2 fumbles, while recording 27 first downs. Up to this point, the Cowboys have amassed 241 passing yards and maintain an average of 127.0 rushing yards.

On defense, Oklahoma State allows an average of 24.0 points per game, ranking 98th nationally. They have conceded a total of 134 rushing yards, along with 2 rushing touchdowns this season. In passing defense, they have relinquished 1 touchdown and 227.0 yards per game, placing them 91st overall. The Cowboys defense has participated in 57 plays, ranking 41st in college football, and they have yet to record any fumbles but have 1 interception this season.

Who will come out on top in this exciting Ducks/Cowboys college football clash?

Prediction: Bet on the Cowboys +22.0

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Pick: Oklahoma State Cowboys +22.0
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