St. Louis Cardinals vs New York Yankees Projection, 8/4/2026 MLB Picks, Top Bets & Odds

Home » St. Louis Cardinals vs New York Yankees Projection, 8/4/2026 MLB Picks, Top Bets & Odds

  • Game: St. Louis Cardinals vs New York Yankees
  • Date: Tuesday, August 4, 2026
  • Venue: Yankee Stadium, Bronx, NY
  • Broadcast: YES Network
  • Odds/Point Spread: St. Louis (+132), New York (-160)

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The New York Yankees (63-49) host the St. Louis Cardinals (55-57) at Yankee Stadium this Tuesday. The betting lines indicate St. Louis at +132, while New York is favored at -160. The over/under for this matchup is set at 9 runs. Expected to pitch are Dustin May for the Cardinals and Ryan Weathers for the Yankees.

MLB Predictions: Lars Nootbaar and St. Louis Cardinals Betting Odds

The Cardinals have a slugging percentage of .375 and have struck out 861 times while drawing 358 walks this season. They have accumulated 470 RBIs with a total of 896 hits, leading to a team batting average of .239. St. Louis has recorded 152 doubles and hit 113 home runs, resulting in 483 total runs and an on-base percentage of .314. With an average of 4.3 runs scored per game, they currently rank 19th in MLB.

St. Louis boasts a team ERA of 4.14, ranking 16th in the MLB, and their pitchers have struck out 856 batters. The staff has surrendered 107 home runs and given up 499 runs total (also 16th in the MLB). They have issued 377 walks, with a collective FIP of 4.07 this season. With 967 hits allowed (averaging 8.7 hits per 9 innings) and 460 earned runs, their K/BB ratio stands at 2.27, complemented by a WHIP of 1.34.

The Cardinals’ bullpen has recorded a save rate of 60.8%, participating in 124 save situations. Thus far, they have secured 31 saves, experiencing 20 failed attempts out of 51. This season, the relievers have inherited 178 base runners, converting 37.1% into scores. The Cardinals’ pitchers have entered with runners on base 123 times and have made 140 appearances in high leverage scenarios, deploying 376 relief pitchers this season. The bullpen has notched 70 holds (8th in MLB).

In 9,003 innings played, the Cardinals have turned 69.2% of balls in play into outs, positioning them 22nd in the league. Defensively, St. Louis has tallied 3,001 putouts, 1,051 assists, and 49 errors, maintaining a fielding percentage of .988, placing them 7th in MLB, alongside 103 double plays.

Dustin May has pitched 433 career innings, recording 403 strikeouts. With a career record of 24-27, he owns a FIP of 3.93 and has faced 1,815 batters in Major League Baseball. His ERA stands at 3.99, having allowed 192 earned runs with a WHIP of 1.222. May has given up 381 hits, averaging 7.9 hits per 9 innings.

The New York Yankees have an on-base percentage of .310 and a batting average of .232 this season. They have struck out 1,022 times (5th in the league) and amassed 862 base hits. The Yankees have hit 157 home runs and accrued 487 RBIs, recording a team slugging percentage of .411, averaging 4.57 runs per game (11th in the league). They have hit 166 doubles and drawn 408 walks, scoring a total of 512 runs.

The Yankees’ pitching staff holds a WHIP of 1.179 and a collective FIP of 3.65 this season. They rank 3rd in the league in hits allowed, with a total of 835 hits given up. Throughout the season, New York’s pitchers have conceded 425 runs, maintaining a solid ERA of 3.28. Their K/BB ratio is an impressive 9.00 (1,001 strikeouts to 342 walks), allowing 107 home runs and yielding 3.83 runs per 9 innings (3rd in the league).

Currently ranked 16th in MLB for save rate (60.8%), the Yankees have used 375 relief pitchers this year. Their relievers entered high leverage situations 132 times, and activated for 134 runners on base. Facing 111 save situations, they’ve achieved 59 holds but have also recorded 20 blown saves. New York has called upon bullpen arms in 51 save chances, netting 31 successful saves. They have inherited 197 base runners, with a scoring conversion rate of 22.8%.

In terms of defensive efficiency, the Yankees lead with a rate of 71.1% (5th in MLB), having executed 82 double plays and holding a fielding percentage of .985 (17th in MLB). They total 980 assists, 61 errors, and 2,996 putouts this season.

Ryan Weathers, in his career, has allowed 400 hits and notched 361 strikeouts over 396 innings pitched. With a WHIP of 1.343 and a FIP of 4.6, he has given up 205 earned runs, yielding a 4.66 ERA while facing 1,694 batters in his MLB journey (16-30 career record).

Who will come out on top tonight in this thrilling MLB matchup against the spread or moneyline?

Prediction: Back St. Louis (+132)

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Pick: St. Louis Cardinals (+132)
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