Cleveland Guardians vs Seattle Mariners Betting Preview, 3/28/2026 MLB Predictions, Picks & Odds

Home » Cleveland Guardians vs Seattle Mariners Betting Preview, 3/28/2026 MLB Predictions, Picks & Odds

  • Matchup: Cleveland Guardians vs Seattle Mariners
  • Date: Saturday, March 28, 2026
  • Venue: T-Mobile Park, Seattle, WA
  • Broadcast: MLB.TV
  • Betting Odds: Cleveland (+102) Seattle (-122)

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On Saturday, March 28, 2026, T-Mobile Park will host the Seattle Mariners (90-72 last season) as they face off against the Cleveland Guardians (88-74 in 2025). The current betting odds have Cleveland at +102 and Seattle at -122, with an over/under set at 8 runs. The starting pitchers are expected to be Joey Cantillo and Bryan Woo.

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Last season, the Guardians recorded a slugging percentage of .373, with 1,344 strikeouts and 494 walks. They tallied 621 RBIs along with 1,199 hits, boasting a team batting average of .226. The Guardians generated 243 doubles and launched 168 home runs, scoring 643 runs with an on-base percentage of .296. Overall, Cleveland averaged 4.0 runs per game, ranking 28th in the league.

In pitching, Cleveland achieved a team ERA of 3.70 (5th in MLB) and struck out 1,381 batters. They allowed 169 home runs and a total of 649 runs (8th). The pitching staff issued 527 walks, concluding the year with a FIP of 3.95. Cleveland permitted 1,291 hits (8.1 hits per 9 innings) and 593 earned runs. Their K/BB ratio was 2.62, with a WHIP of 1.26.

The Guardians’ bullpen faced runners on base 151 times and appeared in 192 high-leverage situations. During the previous season, they secured 112 holds—ranking 2nd in the league—and recorded a save percentage of 68.1%, with 47 saves from 69 chances. They inherited 209 runners, with 32.5% of them scoring. Cleveland’s bullpen saw action from 531 relief pitchers.

Defensively, the Guardians converted 69.8% of balls in play into outs over 12,978 innings, placing 17th in the major leagues. Last season, they achieved 4,326 putouts, 1,330 assists, 99 errors, and a fielding percentage of .985, ranking 21st in MLB while executing 121 double plays.

Joey Cantillo brings a career record of 7-7, having pitched 133 innings with 152 strikeouts. His FIP stands at 3.66, facing 564 batters with an ERA of 3.71 (55 earned runs). Cantillo’s career WHIP is 1.275, allowing 113 hits (7.6 hits per nine innings) and issuing 57 walks.

Meanwhile, the Seattle Mariners recorded a slugging percentage of .420, scoring an average of 4.73 runs per game (10th in MLB). They hit 234 doubles, walked 544 times, and amassed a total of 766 runs, including 238 home runs and 734 RBIs. The Mariners struck out 1,446 times (6th in MLB) and accumulated 1,345 hits, with a team on-base percentage of .320 and a batting average of .244.

Seattle’s pitching staff posted a WHIP of 1.221 and a team FIP of 3.98. They had a strikeout-to-walk ratio of 8.80, allowing 1,331 hits and 192 home runs, with an average of 4.27 runs allowed per 9 innings (13th in MLB). Their ERA stood at 3.87, resulting in 694 runs (629 earned runs) permitted last season.

In relief situations, Mariners’ relievers inherited 25.2% of 147 base runners. They featured in 216 high-leverage instances and faced runners on base 132 times. By season’s end, they had 159 save situations, accumulating 90 holds and 26 blown saves. Their save rate of 62.3% placed them 19th in the league, as the Mariners used 550 different relief pitchers.

In their 13,164 innings played, the Mariners achieved a defensive efficiency of 70.3% (12th in MLB). They recorded 118 double plays with a fielding percentage of .988, ranking 7th in professional baseball, and accounted for 1,355 assists, 69 errors, and 4,388 putouts throughout the year.

Bryan Woo, boasting a career record of 28-15, owns an impressive 3.21 ERA, allowing 7.0 hits every 9 innings. With a K/BB ratio of 4.90, he has faced 1,574 total batters. Woo has given up 141 earned runs, holding a WHIP of 0.982 and a FIP of 3.2. Throughout his career, he has permitted 308 hits while achieving 392 strikeouts over 395 innings.

Who will emerge victorious in this MLB matchup against the spread or moneyline?

Prediction: Bet on Cleveland (+102)

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Pick: Cleveland Guardians (+102)
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