- Matchup: Chicago Cubs vs San Diego Padres
- Date: Monday, April 27, 2026
- Venue: Petco Park, San Diego, CA
- Broadcast: Padres.TV
- Betting Odds: Chicago (-132) San Diego (+110)
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On Monday, the San Diego Padres (18-8) will host the Chicago Cubs (17-10) at Petco Park. The betting line for this game has the Cubs pegged at -132 while the Padres are at +110, with an over/under set at 8.5 runs. The anticipated starting pitchers are Matthew Boyd for the Cubs and Randy Vasquez for the Padres.

The Chicago Cubs are currently averaging 5.5 runs per game, ranking them 3rd in the league. With a total of 149 runs scored and an on-base percentage of .355, they’ve achieved 40 doubles and hit 37 home runs. The team also boasts 135 RBIs and 250 hits this season, with a batting average of .268 and a slugging percentage of .436. They’ve been struck out 231 times while drawing 120 walks.
The Cubs pitching staff has achieved a K/BB ratio of 2.61 and holds a WHIP of 1.19. They have allowed 31 home runs and a total of 112 runs, ranking 10th in the league. Chicago has given up 204 hits (averaging 7.6 hits per 9 innings) and 102 earned runs, landing a team ERA of 3.79 (9th in the league), while notching 217 strikeouts. They have issued 83 walks, with a team FIP of 4.16 over the course of the season.
Cubs pitchers have faced runners on base 28 times, with 24 of those instances being in critical situations. Their relief corps has recorded 4 holds this season (ranking 30th in the league), achieving a save rate of 50.0% out of 14 save situations, successfully converting 5 saves while missing 5 opportunities. The bullpen has inherited 36 runners and allowed 30.6% of those runners to score. A total of 81 relief pitchers have taken the mound this season for the Cubs.
Defensively, the Cubs have compiled 726 putouts, 244 assists, and 14 errors, with a fielding percentage of .986, placing them 14th in MLB. They’ve successfully turned 20 double plays and converted 72.4% of balls put into play into outs across 2,178 innings, ranking 3rd in the league.
Matthew Boyd has pitched 1,102 innings across his career, accumulating 1,067 strikeouts. His career ERA stands at 4.59 (allowing 562 earned runs) with a WHIP of 1.275. He has permitted 1,066 hits and 339 walks, holding a record of 61-78 along with a FIP of 4.52 against 4,670 batters faced.
The Padres have managed a team slugging percentage of .373 and score an average of 4.46 runs per game (16th in baseball). They’ve hit 49 double plays, drawn 92 walks, and scored 116 runs. With 22 home runs and 111 RBIs recorded this season, they have struck out 216 times (23rd in the league) and accumulated 200 base hits. The team holds an on-base percentage of .310 and a batting average of .233.
San Diego’s team WHIP is 1.253, with a cumulative FIP of 3.38 this season. Ranking 9th in the league for hits allowed, they’ve given up 207 hits in total, resulting in 99 runs scored against them, with an impressive ERA of 3.63 (94 earned runs). Their strikeout to walk ratio is an impressive 9.00, tallying 234 strikeouts against 85 walks. Allowing only 17 home runs, they concede 3.82 runs per 9 innings, ranking 4th in the league.
In terms of saves, they are 8th in MLB with a save rate of 70.6%, having utilized 88 relievers this season. Their bullpen has seen action in 31 high-pressure situations and 23 times with runners on base. Out of 40 save opportunities, the Padres have achieved 21 holds, with 5 blown saves, successfully converting 12 of their save chances. The relievers have seen an inherited runner score 38.1% of the time this season.
In 2,097 innings played, the Padres have a defensive efficiency rate of 69.1% (19th in the league). Fielding at .992 (3rd in MLB), they’ve turned 22 double plays and recorded 699 putouts alongside 7 errors and 227 assists this season.
Randy Vasquez has allowed 297 hits while accumulating 203 strikeouts in 297 innings pitched during his career. His career stats include 128 earned runs allowed, a WHIP of 1.359, and a FIP of 3.8. He has a K/BB ratio of 1.90 and has faced 1,281 batters, holding a record of 14-16 with a 3.87 ERA (averaging 9.0 hits per inning).
Who will emerge victorious in tonight’s MLB contest against the spread or on the moneyline?
Prediction: Back Chicago (-132)
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