- Matchup: Milwaukee Brewers vs. St. Louis Cardinals
- Date: Wednesday, May 6, 2026
- Venue: Busch Stadium, St. Louis, MO
- Broadcast: Cardinals.TV
- Odds/Point Spread: Milwaukee (-145) St. Louis (+125)
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On Wednesday, the St. Louis Cardinals (21-14) will aim to best the Milwaukee Brewers (18-16) at Busch Stadium. The betting odds feature Milwaukee at -145, while St. Louis opens at +125. The total runs projected for this game stand at 8. Scheduled to pitch are Jacob Misiorowski for Milwaukee and Matthew Liberatore for St. Louis.

The Brewers have smashed 56 doubles and launched 23 home runs as a team. Currently, Milwaukee boasts a slugging percentage of .358 while racking up 269 strikeouts compared to 159 walks. Averaging 5.2 runs per game places them 5th in Major League Baseball. With 168 RBIs and 275 hits this season, their batting average stands at .241, supporting a total of 175 runs and an on-base percentage of .336.
The Brewers currently maintain a team ERA of 3.64, ranking 4th in the league, with their pitchers striking out 318 batters. Milwaukee’s pitchers have surrendered 28 home runs and 133 runs total (5th in MLB). They have a control issue with 122 walks, and their FIP is 3.56. The team has given up 261 hits, averaging 7.8 hits per 9 innings, alongside 122 earned runs. They hold a K/BB ratio of 2.61 and a WHIP of 1.27.
This season, the Brewers have used 114 relief pitchers. Their bullpen has inherited 51 runners, with 37.3% of those scoring. Recording 20 holds places them at 16th in the league; Brewers’ pitchers have entered with runners on base 33 times and faced high-leverage situations 35 times. They’ve achieved 10 saves out of 15 opportunities, resulting in a save rate of 66.7% in 36 save situations.
At this stage of the season, the Milwaukee Brewers have recorded 904 putouts, 279 assists, and 16 errors. Their fielding percentage is a solid .987, ranking 10th in the league, with 27 double plays completed. They convert 69.1% of balls in play into outs over 2,712 innings, placing them 22nd in MLB.
Misiorowski has pitched 104 innings during his MLB career, boasting 146 strikeouts. With a career record of 7-5, his FIP is 3.75, and he has faced 428 batters, yielding a 3.81 earned run average (44 ER) and a WHIP of 1.154. He’s allowed 74 hits, averaging 6.4 hits per nine innings, alongside issuing 46 walks.
The St. Louis Cardinals are currently at an OBP of .327, with a team batting average of .243. They’ve struck out 292 times (15th in MLB) and recorded 286 hits. St. Louis has belted 44 home runs, accumulating 168 RBIs. Their slugging percentage sits at .404, scoring an average of 4.91 runs per game (9th in the league). They have 55 doubles, 127 walks, and a total of 172 runs scored.
The Cardinals possess a WHIP of 1.427, and their pitching staff has a FIP of 4.62 this season. The team’s K/BB ratio is notably favorable at 6.90 (243 strikeouts against 134 walks), but they are ranked 25th in total hits allowed with 317. They’ve surrendered 38 home runs, allowing 4.81 runs per 9 innings (21st in MLB), resulting in a team ERA of 4.50 after 169 runs given up.
Boasting a save percentage of 68.4%, the Cardinals have utilized 129 relief pitchers this year. Their relievers have appeared in high-pressure situations 45 times and faced base runners 40 times. St. Louis’ 51 save situations have resulted in 30 holds and six blown saves, with the bullpen converting 13 out of 19 save opportunities.
Having played 2,844 innings, the Cardinals’ defensive efficiency is 69.2% (20th in MLB). This season, the St. Louis Cardinals have achieved 36 double plays and possess a fielding rate of .986 (14th in MLB). They’ve completed 355 assists, made 18 errors, and recorded 948 putouts up to this point.
Liberatore, with a career win-loss record of 17-25, holds a 4.62 ERA and gives up 9.4 hits per 9 innings. His strikeout to walk ratio is 2.38, having faced 1,600 batters in his career. Liberatore has allowed 190 earned runs with a WHIP of 1.384 and a FIP of 4.6. In 370 innings pitched, he has given up 388 hits while registering 295 strikeouts.
Who do you think will emerge victorious in tonight’s MLB matchup against the spread or moneyline?
Prediction: Back St. Louis (+125)
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