- Matchup: Pittsburgh Pirates vs Cincinnati Reds
- Event Date: Wednesday, September 24, 2025
- Venue: Great American Ball Park, Cincinnati, OH
- Broadcast: FanDuel Sports Network Ohio
- Betting Odds: Pittsburgh (+132) Cincinnati (-160)
This page may include affiliate links at no extra cost to you, thanks for your support.
The Pittsburgh Pirates (67-89) are heading to Great American Ball Park on Wednesday as they aim to take down the Cincinnati Reds (80-76). The current odds position the Pirates at +132, while the Reds are line-up at -160. The total run line for the game is set at 8, with Paul Skenes and Hunter Greene taking the mound as starting pitchers.

This season, the Pittsburgh Pirates are scoring an average of 3.6 runs per game, placing them at 30th in the league. To date, they have accumulated a total of 561 runs and maintain a team on-base percentage (OBP) of .305. The Pirates have recorded 233 doubles and hit 112 home runs, totaling 540 RBIs and 1,195 hits, with a batting average of .231. Their slugging percentage is .350, with 1,364 strikeouts and 515 walks.
The Pirates are currently posting a team ERA of 3.82, ranking 8th in the league, while their pitchers have struck out 1,254 batters. Pittsburgh’s staff has conceded 147 home runs and 630 total runs, placing them 7th in MLB. Their pitchers have walked 456 batters, with a collective FIP of 3.86. With 1,223 hits allowed (8.0 per 9 innings), they have conceded 585 earned runs, achieving a K/BB ratio of 2.75 and a team WHIP of 1.22.
This season, Pittsburgh has utilized 488 relief pitchers. The bullpen has inherited 211 base runners, with 36.5% scoring, and has achieved 34 saves while failing on 24 out of 58 opportunities. They hold a save rate of 58.6% and have made 127 appearances in save situations, accumulating 67 holds (ranked 27th in the league). Pirates hurlers have entered games with opposing runners on base 137 times, facing 149 high-leverage situations.
As of now, the Pittsburgh Pirates have collected 4,130 putouts, 1,288 assists, and committed 75 errors, showcasing a fielding percentage of .986, ranking them 14th in MLB. They have executed 112 double plays, converting 70.7% of balls in play into outs across 12,390 innings, placing them 8th overall.
Paul Skenes has pitched 314 total innings, racking up 379 strikeouts. He has an impressive earned run average of 2.01 (70 earned runs allowed) and a WHIP of 0.955. Allowing 226 hits (6.5 hits per 9 innings), he has also issued 74 walks. Skenes boasts a 21-13 career win-loss record, with a FIP of 1.98 while facing 1,225 hitters in professional baseball.
The Cincinnati Reds are achieving a team slugging percentage of .392, scoring an average of 4.47 runs per game (14th in the league). They’ve managed 243 doubles while walking 508 times and generating 697 total runs. Cincinnati has hit 161 home runs this season, accumulating 659 RBIs. They have struck out 1,353 times (9th in the league) and achieved 1,284 hits, sitting at a team OBP of .315 and a batting average of .245.
Defensively, the Reds hold a team WHIP of 1.233 and a FIP of 4.17. They rank 8th in the league for total hits allowed, with 1,224 given up. The Cincinnati pitching staff has allowed 663 runs for the year, maintaining a team ERA of 3.91 (600 earned runs). They’re working with a strikeout-to-walk ratio of 8.60 (1,319 strikeouts to 477 walks), surrendering 187 home runs and conceding 4.32 runs per 9 innings (14th in MLB).
In terms of relief efforts, the Reds have encountered 161 save situations and secured 98 holds alongside 22 blown saves. They’ve called upon their bullpen 60 times in save chances, successfully converting 38. Their relief pitchers have appeared 164 times in high-leverage scenarios and 142 times with runners on base. Cincinnati’s inherited scoring rate stands at 32.5%, granting them a 63.3% save rate (17th in the league) with 528 relief pitchers deployed this season.
On the defensive end, the Cincinnati Reds have achieved 97 double plays and hold a fielding percentage of .984 (22nd in professional baseball). They have accrued 1,195 assists, 85 errors, and 4,140 putouts thus far this season. Across 12,420 innings on the field, the Reds exhibit a defensive efficiency of 71.0% (4th in baseball).
Greene (25-29 career record) presents a 3.66 earned run average while allowing 7.0 hits per 9 innings. His strikeout-to-walk ratio is 3.45, having faced 2,037 batters in his MLB career. He’s yielded 199 earned runs, holding a WHIP of 1.141 and a FIP of 3.6. Throughout his career, Greene has allowed 381 hits while accumulating 610 strikeouts over 489 innings pitched.
Who will emerge victorious in tonight’s MLB matchup against the spread or moneyline?
Prediction: Take Cincinnati (-160)
Some links on this page are affiliate links. If you sign up or make a purchase through them, we may earn a small commission always at no extra cost to you. Thanks for helping us keep this site running.
