- Matchup: San Francisco Giants vs Cincinnati Reds
- Date: Wednesday, April 15, 2026
- Venue: Great American Ball Park, Cincinnati, OH
- Broadcast: Reds.TV
- Betting Lines: San Francisco (+150) Cincinnati (-182)
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The San Francisco Giants (6-10) are set to visit Great American Ball Park on Wednesday, taking on the Cincinnati Reds (9-7). The moneyline favors the Giants at +150 while the Reds open at -182, with a total set at 8 runs. Key starters expected are Tyler Mahle and Rhett Lowder.

The Giants are experiencing a season with a slugging percentage of .357, having struck out 123 times and drawn only 33 walks. They have accumulated 48 RBIs and achieved 129 hits, holding a team batting average of .243. Together, the Giants have hit 28 doubles and launched 8 home runs, totaling 51 runs with an on-base percentage of .288. Averaging 3.2 runs per game, San Francisco ranks 29th in baseball.
San Francisco’s pitching staff holds a K/BB ratio of 2.28 with a cumulative WHIP of 1.39. They have allowed 14 home runs and a total of 72 runs (ranking 23rd in MLB). The Giants have given up 135 base hits at an average of 8.6 hits per 9 innings, with 67 earned runs leading to a year ERA of 4.28 (23rd overall), while successfully striking out 139 batters. They have issued 61 walks and possess a team FIP of 3.80 this season.
The bullpen has a save success rate of 50.0% in 10 save situations, securing 2 saves and blowing 2 out of 4 opportunities. This season, the relievers have inherited 32 base runners, with 31.3% allowing a run. They have faced runners on base 19 times and encountered high-leverage situations 4 times, using 55 different relief pitchers. The bullpen recorded 6 holds this season (25th in MLB).
Defensively, the Giants have converted 67.5% of opportunities into outs over 1,269 innings, placing them at 27th in the league. The Seattle Mariners have achieved 423 putouts this season, alongside 153 assists and 10 errors. With a fielding percentage of .983, the Giants rank 22nd in the majors and have completed 16 double plays.
Tyler Mahle, with a career record of 39-48, has a FIP of 4.01 and faced a total of 3,186 hitters in the majors. He has allowed 697 hits (averaging 8.4 hits per nine innings) and tallied 271 walks. His career ERA stands at 4.07, having given up 339 earned runs and posting a WHIP of 1.292 over 749 innings pitched, which includes 768 strikeouts.
The Reds are hitting with a team slugging percentage of .325 and averaging 3.38 runs per game (27th in the league). They have 17 doubles, 69 walks, and a total of 54 runs. Cincinnati has hit 15 home runs this season along with 46 RBIs and has struck out 145 times (8th in MLB), achieving 109 total hits. Their team OBP sits at .298, accompanied by a batting average of .205.
As a pitching unit, the Reds have posted a WHIP of 1.400 and a FIP of 4.54. They rank 19th in allowing hits with 125. Cincinnati’s pitchers have permitted 70 runs this season, leading to a 4.03 ERA (65 earned runs). Their strikeout-to-walk ratio stands at 8.00 (129 strikeouts vs 78 walks), allowing 16 home runs while conceding 4.34 runs per nine innings (15th in MLB).
With a save success rate of 75.0%, they have deployed 61 relievers this season. Their bullpen has been in high-leverage situations 23 times and faced runners on base 21 occasions. With 24 save opportunities, they’ve secured 15 holds and dropped 2 saves. The bullpen has recorded 6 saves in 8 opportunities, with an inherited score percentage of 20.7% from 29 inherited runners.
Defensively, the Cincinnati Reds have completed 15 double plays, boasting a fielding percentage of .988 (9th in MLB), with 139 assists, 7 errors, and 435 putouts this season. Their fielding efficiency stands at 71.6% over 1,305 innings (6th in MLB).
In his professional career, Lowder has allowed 39 hits, with 33 strikeouts over 46 innings pitched. He has given up 10 earned runs, possesses a WHIP of 1.274, and has a FIP of 1.9. His strikeout-to-walk ratio is 1.65, facing 197 batters in total. Lowder, with a career record of 3-3, holds a 1.94 ERA and allows 7.6 hits per nine innings pitched.
Who do you think will emerge victorious in tonight’s MLB contest—against the spread or on the moneyline?
Prediction: Back Cincinnati (-182)
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